MaaT Pharma to Announce Clinical Data with its Lead Microbiota Biotherapeutic in Intestinal Acute GvHD at Virtual 46th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT)
- Data from the Company’s compassionate use program with MaaT013 as a treatment in patients with intestinal acute Graft-versus-Host-Disease will be highlighted in an e-poster presentation
- MaaT013 is an enema formulation of a microbiota biotherapeutic characterized by consistently high diversity and richness of microbial species derived from pooled healthy donors
- Results will be announced on Monday, August 31
LYON, France: MaaT Pharma announced today that clinical data from 11 patients treated with the company’s lead microbiome restoration biotherapeutic, MaaT013, will be presented in an e-poster at the 46th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) to be held virtually from August 29 – September 1, 2020. MaaT013 is an enema formulation of a microbiota biotherapeutic characterized by a consistent richness of microbial species derived from pooled healthy donors to treat patients with intestinal acute Graft-versus-Host-Disease (aGvHD) following allogeneic Hematopoietic Stem-Cell Transplantation (allo-HSCT). MaaT Pharma provided MaaT013 to hospitals as part of its compassionate use program for patients who had previously received and failed up to five previous systemic treatments for GvHD. MaaT Pharma will share the results through a press release on Monday, August 31, 2020.
As the event is held virtually this year, the presentation will take the form of an e-poster with commentary. The abstract of the presentation is available using the following link, https://www.professionalabstracts.com/ebmt2020/iPlanner/#/presentation/5171.
e-Poster presentation details:
Title: Successful and Safe Treatment of Intestinal Graft-Versus-Host Disease (GvHD) with Pooled-Donor Full Ecosystem Microbiota Biotherapeutics
Presenter: Dr. Florent Malard, Associate Professor of Hematology at the Saint-Antoine Hospital and Sorbonne University
Session Name: e-Experimental Transplantation
Date/Time: Saturday, August 29, 2020 / 12:30 PM – 06:30 PM CET
Location: e-Poster area
In addition to the compassionate use program, MaaT Pharma is currently investigating MaaT013 in a multi-center, single-arm, open-label, Phase II clinical trial called HERACLES to evaluate the safety and efficacy of MaaT013 in gastrointestinal-predominant, steroid-refactory, acute GvHD (GI SR-aGvHD) patients. The acute form of GvHD is a serious, often fatal syndrome typically involving the gut, skin and liver. MaaT Pharma has established the most complete approach to restoring patient-microbiome symbiosis in the gut to improve efficacy of cancer treatments and survival outcomes in life-threatening diseases. MaaT013 has been granted Orphan Drug Designation by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA).
